The Universidad Autónoma de Santo Domingo (UASD) (Autonomous University of Santo Domingo) is the public university system in the Dominican Republic with its flagship campus in the Ciudad Universitaria of Santo Domingo and with regional campuses in many cities of the Republic. It was reopened and renamed in 1914, replacing the former Universidad Santo Tomás de Aquino, the first university of the Western Hemisphere (Americas), which was founded unofficially by a Papal bull in 1538, officially by royal decree in 1558, and closed in 1832.

In structure, the school followed the model of the University of Alcalá de Henares. The university organized its offerings into four schools: Medicine, Law, Theology, and the Arts. Today, the University has expanded to eight schools: Humanities, the Arts, Law and Political Science, Health Sciences, Economics and Social Sciences, Science, Engineering and Architecture, and Agricultural Sciences.

Universidad Católica Santo Domingo (La Católica) – UCSD (Santo Domingo Catholic University) is a private Catholic university located in the archdiocese of Santo Domingo, in the Dominican Republic. The university was first established in 1982, with 65 students first entering the school in the following year.

The university currently contains over 5,000 students and 250 faculty members. It is one of the private universities in Santo Domingo, but it is commonly known as "La Católica", and its population is mostly middle-class students who work and study full-time, and pay their own tuition. The professors are good, and most of the classes are relatively small, so it ensures individualized attention in the learning process. It is mostly known for its Education program, and its Business Faculty, recently also the faculties of both Communications and Publicity [Advertising] have been gaining their place in the university market.

Faculties: Diplomacy and International Relations; Odontology or Dentistry; Engineering system; Architecture; Economics; Psychology; Faculty of Law; Tourism; Social communication; Administration; Physiotherapy, Marketing...

The University has a sport department which they look forward to have completely developed with a tremendous soccer team (currently Prof. Jaime Paez head coach, Lendz Heriveaux coach assistant and Serge Junior Fecu captain); it also has a basketball team; then a Volleyball one. After the creation of the soccer team, they have participated in some nearby tournaments, such as the one done by the Sports Ministry(inter Universities) and they ended up having the most valuable player of the whole tournament in the name of Stephano Reyes. They right after ended up at the second position in another tournament done by the Universidad Tecnologica de santiago (UTESA). The team has a stunning diversity, combined with some motivated Haitians, in the majority, Dominicans, Venezuelans and Colombians. They play both Futsal and regular soccer (big field).

Universidad Católica Santo Domingo (UCSD) is a university in Santo Domingo in the Dominican Republic.

The Universidad Católica Tecnológica del Cibao (UCATECI) (Technological Catholic University of the Cibao) is a private university in the Dominican Republic with its main campus in La Vega[disambiguation needed]. It was formerly known as Universidad Tecnológica del Cibao (UTECI).

Universidad de la Tercera Edad (UTE) is a university in Santo Domingo in the Dominican Republic.

Instituto Politécnico Loyola (Loyola Polytechnic Institute or IPL) is located in San Cristóbal, Dominican Republic. It is known for its agronomists. It offers technical careers in Agronomy, Mechanics, Electronics, Electricity, etc. Its rector is José Núñez Mármol, SJ. The colors of the IPL for grades are: Sky Blue for 9th Grade, blue for 10th Grade, light yellow for 11th Grade and beige for 12th grade.

Universidad Federico Henríquez y Carvajal (UFHEC) is a university in Santo Domingo in the Dominican Republic.

In the United States, the California medical boards has listed UNIREMOS as an institution whose graduates are ineligible for licensure.

Instituto Tecnológico de las Américas (ITLA) is a university in Santo Domingo in the Dominican Republic.

Universidad Instituto Cultural Domínico Americano (UNICDA) is a university in Santo Domingo in the Dominican Republic.

Intec College is a distance education centre located in South Africa. They are associated with the International Correspondence School, founded in the United States in 1896. The Cape Town branch was founded in 1906, which is the branch associated with Intec College.

Intec college offers 300+ courses. They are divided into schools, including the Business School, Technical Studies, Vocational School, and others. They claim more than 120,000 active students, and have students ranging in age from 14 to 90.